Expression, secretion and antigenic variation of bacterial S-layer proteins
نویسندگان
چکیده
منابع مشابه
Genetic mechanisms of bacterial antigenic variation.
The ability of an organism to respond and adapt to the environment is the keystone to its survival as a species. Pathogenic microorganisms have evolved a variety of mechanisms to deal with the rigors of the host immune response. These mechanisms, depending on the life cycle of the pathogen, include mimicry of host antigens, survival within professional phagocytes, and antigenic variation of maj...
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Background: Hepatitis C virus (HCV) is a main public health problem causing chronic liver infection and subsequently liver cirrhosis and lethal hepatocellular carcinoma (HCC). Vaccination based on HCV capsid proteins has attracted a special interest for prevention of viral infections. The core protein is a basic and evolutionary most conserved protein, which regulates the cellular processes rel...
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Objective(s): Helicobacter pylori, a human specific gastric pathogen is a causative agent of chronic active gastritis. The vacuolating cytotoxin (VacA) is an effective virulence factor involved in gastric injury. The aim of this study was to construct a recombinant protein containing antigenic region of VacA gene and determine its antigenicity. Materials and Methods: The antigenic region of V...
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Many bacterial pathogens are exquisitely adapted to host parasitization. Their niche is primarily determined by the biochemical milieu of the host. As such, pathogens are selected to exhibit environmentally responsive and adaptive molecular traits which allow adherence, entrance, and replication within the host (7, 26). One major set of selective forces which operates to shape the phenotype of ...
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ژورنال
عنوان ژورنال: Molecular Microbiology
سال: 1996
ISSN: 0950-382X,1365-2958
DOI: 10.1046/j.1365-2958.1996.711442.x